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Thursday, September 30, 2021

Another child dies of COVID in Virginia - WWBT NBC12 News

PORTSMOUTH, Va. (WWBT) - Another child under the age of 10 died of COVID-19 in Virginia, NBC affiliate WAVY reports.

The child who died was in the Eastern health region, VDH told WAVY. Additional details were not released to protect the privacy of the child and family.

This comes the day after WAVY reported the death of 10-year-old Teresa Sperry, whose family said she died of COVID.

The Virginia Department of Health is reporting that five children under the age of 10 have died of COVID, while eight children ages 10-19 have died of the virus.

Copyright 2021 WWBT. All rights reserved.

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It's flu vaccine time, even if you've had your COVID shots - Yahoo! Voices

Amid all the focus on COVID-19 vaccinations, U.S. health experts have another plea: Don’t skip your flu shot.

Flu cases have dropped to historically low levels during the pandemic. The U.S. and Europe experienced hardly any flu last winter, and the Southern Hemisphere just ended its second flu season of the coronavirus pandemic with little to report.

But with U.S. schools and businesses reopened, international travel resuming and far less masking this fall, flu could make a comeback. The big question is whether it will trickle in or roar back and put extra pressure on hospitals already struggling with COVID-19 surges.

“People are sick to death of hearing about having to roll on out and get vaccines of any sort,” said flu specialist Richard Webby of St. Jude Children’s Research Hospital in Memphis. 

Yet after 18 months of little influenza exposure, “we probably as a population don’t have as much immunity against this virus as we typically might,” Webby said. “It makes absolute sense to go on out and get that vaccine and at least prepare for something that, you know, could be quite severe.”

Here are some things to know:

Q: Who should get a flu vaccine?

A: The Centers for Disease Control and Prevention says just about everybody needs an annual flu vaccination, starting with 6-month-old babies. Influenza is most dangerous for adults over age 65, young children, pregnant women and people with certain health conditions, such as heart or lung disease.

Q: Why do I need one this year, since flu hasn’t been a threat during the pandemic?

A: COVID-19 restrictions including masking and staying home — especially for children, who are flu’s biggest spreaders — clearly had a side benefit of tamping down influenza and other respiratory bugs. But as soon as masks started to come off, the U.S. experienced an unusual summer surge of children hospitalized with a different virus, named RSV, that usually strikes in the winter. That’s a worrying sign of what to expect if flu returns.

Q: What’s the forecast for flu this winter?

A: Flu is notoriously difficult to predict. But there’s a little more circulating in some countries this fall than last, including a recent uptick in China, said Webby, who directs a World Health Organization flu center. And people may be a little more vulnerable: Before the pandemic, 15% to 30% of the population was exposed to flu each year, a missing bump in immunity, he said.

“If flu does at least get a foothold in, it’s going to have more opportunity of spreading this season,” he said.

Q: When should I get a flu vaccine?

A: Now. The CDC encourages people to get their vaccine by the end of October. Doctors' offices, retail pharmacies and local health departments have millions of doses in hand. And most Americans with health insurance can get it with no co-pay.

Q: I already got a COVID-19 vaccine. Do I really need a flu shot, too?

A: COVID-19 vaccines prevent the coronavirus and flu vaccines prevent influenza. They don’t overlap. But you can catch both viruses at the same time, or one after the other.

“Avoid the double whammy” and get both vaccines, advised the American College of Emergency Physicians. For now, COVID-19 vaccines are available for anyone 12 and older.

Flu vaccines aren’t as powerful as vaccines against some other diseases but if people do get influenza anyway, they tend to have a much milder illness.

Q: Can I get a flu vaccine and a COVID-19 vaccine at the same visit?

A: Yes, the CDC says it’s fine to pair a flu vaccine with either a primary COVID-19 shot or a booster dose. 

Q: What’s the best flu vaccine to get?

A: Flu constantly evolves, and each year’s vaccine is made to fight the strains that international experts deem most likely to circulate. This year all the flu vaccines offered in the U.S. offer protection against all four of those strains. Options include traditional shots or a nasal spray vaccine. There also are shots specifically designed to rev up seniors’ age-weakened immune systems, either with a higher dose or an added immune booster. There are also options for people allergic to eggs, which are used to make some flu shots.

Q: How much flu vaccine is available?

A: The CDC expects vaccine manufacturers to deliver 188 million to 200 million doses. Nearly 194 million doses were distributed last winter, a record.

___

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.

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Biden team’s booster divide deepens as risk of winter virus surge looms - POLITICO

President Joe Biden’s top health advisers are split over the role booster shots should play in the next phase of the pandemic, setting up key fault lines to close in the coming weeks as they try to ward off further surges this fall and winter.

Their disagreement centers on whether the U.S. should eventually offer an additional shot to every vaccinated adult in hopes of preventing even mild and moderate symptomatic breakthrough infections, according to three senior health officials and two people familiar with the government’s internal discussions.

The Biden team’s deliberations have intensified in recent days, as officials scrutinize the incomplete and sometimes conflicting data on vaccines’ performance. One group, including some scientists at the Centers for Disease Control and Prevention and the Food and Drug Administration, argues that boosters aren’t capable of blocking all infection, the sources said. They think additional vaccine doses should be given only as needed to reduce cases of severe illness and death. Another group — including Biden’s chief medical adviser, Anthony Fauci — says the government should not rule out using boosters to help stave off even mild Covid-19 infections that can keep people out of work for weeks.

Whatever decisions health officials make will have major implications for the course of the pandemic in the coming months, when the combination of colder weather and holiday gatherings is poised to fuel the virus’ spread. The growing tension among the president’s top Covid-19 advisers raises questions about whether the goals of the nation’s vaccination campaign are changing, and the degree to which breakthrough infections may be inevitable. It comes as many scientists warn that while the pandemic will eventually end, the virus itself will remain a significant presence for years to come.

“We are in a vulnerable position,” said Eric Topol, a professor of molecular medicine at Scripps Research. “We’re very much under-vaccinated. We're also one of the countries that whatever vaccination rate we achieve, we got most of it early, so a lot of those people are now becoming vulnerable. That doesn't portend a nice descent ramp from Delta.”

The White House, CDC and the Department of Health and Human Services declined to comment. A senior administration official pointed to recent comments by Fauci and CDC Director Rochelle Walensky endorsing the idea that even mild breakthrough infections are of concern.

For months, administration officials have grappled with how to interpret and respond to domestic and international data that suggest available vaccines’ effectiveness against infection, and in some cases hospitalization, is beginning to wane.

Biden’s team originally aimed to offer boosters to all adults starting the week of Sept. 20. But the administration scaled back its vision amid pushback from scientists at the FDA and CDC and on the agencies’ outside advisory committees. They objected because of the limited CDC studies on vaccine performance did not prove definitively that large portions of the country were in immediate need of a booster — or how long the benefit from a booster would last.

For now, the FDA and the CDC recommend boosters only for certain people who originally received the Pfizer-BioNTech vaccine — including those 65 and older, and people over 18 with underlying health conditions or jobs that increase their risk of severe Covid-19. But federal officials are already weighing which groups might be next in line for boosters this fall and winter as cold weather drives people to spend more time indoors.

The current conversations about how to prepare for the potential rise in cases come at a tenuous time for the administration and its pandemic response.

The highly contagious Delta variant continues to spread across the country. Health experts are warning that the country could see another surge, especially if vaccine efficacy falls off dramatically over the next several months as it did in Israel. But federal officials do not have solid data, particularly domestic data, that spells out exactly how long boosters last and which populations would benefit. That muddies any risk-benefit calculations.

But waiting for definitive findings before making the shots widely available could have its own cost, said Leana Wen, an emergency physician and public health professor at George Washington University.

“I don't think that the federal government should be in the business of telling people what is valuable to them. I don't need the federal government telling me that I shouldn't care about infecting my young, vulnerable family members,” she said. “That's why the CDC meeting last week was so frustrating because they were basically saying, ‘We know better than you do about preventing or about what's important to you.’”

And the difficulty of forecasting how the U.S. outbreak will behave over the next several months increases the policy challenge facing the Biden administration. Senior federal officials are essentially trying to predict the unknowable. The big question for many members of Biden’s Covid team is whether the U.S. should give boosters to otherwise healthy Americans to help reduce transmission and infection, limit boosters until most of the world receives its first dose or try to do both at once. The answers vary widely.

“I don’t think anything is an open-and-shut case right now. I think things are suggestive,” said Craig Spencer, an emergency medicine doctor at New York University, of vaccine efficacy data. “Will [boosters] be justified? I think that depends on what you think we should be doing with our vaccines. We're sitting on hundreds of millions of doses that could immediately be used in places to stop the spread and stop people from dying from a largely vaccine-preventable illness.”

The Biden administration faced immediate backlash in August when it announced that it would begin offering booster shots in September. Health experts and international officials said the U.S. should do more to help vaccinate the rest of the world before it moved forward with an additional dose for Americans. Medical and public-health experts with connections to the White House, including former Biden transition team members, also argued that available data showed vaccines still did a good job preventing severe disease and death, even if their power to prevent mild infection was waning.

That criticism kicked off a series of conversations within the White House and among Biden Covid-19 officials about how best to get ahead of a potential surge as the pandemic nears the end of its second year.

Scientists at the CDC and the FDA, and the agencies’ external advisers, made clear in recent presentations that boosters would not necessarily prevent mild infection. They argued that the shots should be used to protect the elderly and other groups for whom vaccination was becoming less effective at warding off hospitalization and death.

Through it all, Fauci has been vocal about his thinking on boosters, saying Israeli data is clear: Vaccine efficacy against mild and moderate illness is decreasing, and boosters are the solution. He argues that the U.S. should not reserve third shots as protection against severe disease, bucking the FDA and CDC’s latest recommendations.

“It seems like [the advisory groups] were saying it is okay as long as you don’t wind up in the hospital and die,” Fauci said in a recent interview with conservative radio talk-show host Hugh Hewitt. “I don’t feel that way. I feel we need to protect not only from getting people in the hospital ... but we don’t want people to get sick. You can also get pretty sick and not necessarily have to go to the hospital.”

Fauci added that his approach was not in conflict with Biden’s goal of helping to vaccinate the world, noting that the administration “is committed to be doing even more” on that front.

Walensky has also noted the importance of finding a way to deal with mild breakthrough infections, even though her agency decided in May to track only cases that resulted in hospitalization. If a health care worker calls in sick with a breakthrough infection “that could be an ICU bed that can’t be filled because they don’t have workforce,” she said recently at the Atlantic Ideas Festival.

But Walensky also said last week at a press conference that getting booster shots is a “walk, don’t run, situation,” stressing that driving up the overall vaccination rate is also a powerful method to protect the vulnerable.

The administration’s internal struggle over boosters continues to spill out into public view as experts search for ways to prevent a repeat of last winter’s devastating surge.

“There's a reluctance to use the third jabs in this country, even though they could help a lot to basically get all those people who are early vaccinated to get them back to fully protected,” Topol said. “We're starting to negate the importance of infections. And that's not good. The other thing that I think is discounted is the long-Covid story. The only prevention of long Covid is to prevent the infection.”

For others like Spencer, the emergency room doctor from New York City, any move to dole out boosters broadly now would gloss over the fact that the U.S. still does not have good data on the shot's benefits — and potential risks.

“Are we ever going to be able to boost people enough so that they have sterilizing immunity, meaning they can't get infected?” Spencer said. “For someone like myself or someone younger ... we don't know what the risk is of a third dose of a vaccine. What is the impact on myocarditis? We don't know. I prefer we know that before we may roll broad policy recommendations, which could ultimately undermine our push to expand vaccines.”

The administration has begun to discuss what other strategies it can recommend or encourage to prevent a spike in infections during the coming holiday season. Possible approaches include revising guidelines for mask wearing and increasing access to rapid Covid-19 testing.

“If we all were doing rapid antigen tests every day or every other day, we would know that but here we have a blind guide to getting those out there to help navigate through this,” Topol said.

Rapid tests are still relatively expensive in the U.S. and are not widely available. Without wide use of strict public health measures like frequent testing, and in light of the country’s relatively low vaccination rate, officials said they are still struggling to develop a long-term pandemic strategy.

“The question for society is what is the level of death we are willing to accept? And what's the price that we're willing to pay?” Wen said. “I think there are some people who might say, 'Hey, it's a win if we can make Covid to be like a flu.' But even then, we're talking about double the flu. Then the question becomes, what is the price we're willing to pay to reduce the level of Covid? Do we actually want to reduce the burden of suffering even more if that requires wearing masks every winter? Are people willing to take on that price?”

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Kaiser doctor explains why pregnant women should get the COVID-19 vaccine, not skip medical visits - KCRA Sacramento

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  1. Kaiser doctor explains why pregnant women should get the COVID-19 vaccine, not skip medical visits  KCRA Sacramento
  2. CDC Issues Urgent Recommendation For Pregnant Women To Get Vaccinated  TODAY
  3. CDC issues an 'urgent' warning for pregnant people to get vaccinated as new data show pregnancy almost doubles the risk of death from COVID-19  Yahoo! Voices
  4. Breakthrough hospitalizations a reflection of Maine's high vaccination rate  Bangor Daily News
  5. CDC urges pregnant women to get vaccinated  KOBI-TV NBC5 / KOTI-TV NBC2
  6. View Full Coverage on Google News
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COVID-19 antiviral pills: Results coming impacting the pandemic - Business Insider

CDC Urges Pregnant People to Get Vaccinated for Covid-19 As Soon as Possible - Gizmodo

A pregnant woman wearing a face mask walks past a street mural in Hong Kong, on March 23, 2020,
A pregnant woman wearing a face mask walks past a street mural in Hong Kong, on March 23, 2020,
Photo: Anthony Wallace/AFP (Getty Images)

Health officials with the Centers for Disease Control and Prevention are pleading with pregnant people to get vaccinated against covid-19. In a new urgent health advisory out this week, the CDC says that only around a third of these individuals have gotten fully vaccinated. Research has shown that the vaccines do not raise the risk of health concerns like miscarriages, while contracting covid-19 can be dangerous for both the parent and fetus.

Prior to their authorization in the U.S. and elsewhere starting late last year, there had been no data collected on the safety of covid-19 vaccines for pregnant people, who have been historically excluded from clinical trials of new drugs and vaccines, often without clear justification. It was a gap that experts had lamented even during the pivotal trials used to secure their authorization, and some warned that it could drive hesitancy among these individuals.

Clinical trials of the vaccines looking specifically at pregnant people have since been started, though none seem to have been completed as of yet. However, real-world data has been collected on the outcomes of pregnant people following vaccination. Research from the CDC and other scientists has found no link between vaccination and an increased risk of adverse pregnancy outcomes like stillbirth, miscarriages, or premature births when compared to the general public. Other studies have even suggested that pregnant people who get vaccinated can then pass along coronavirus-specific antibodies to their fetus in the womb or to their newborns through breastfeeding, offering some amount of temporary protection in the event they catch covid-19. Vaccination is recommended for anyone who’s pregnant, considering pregnancy, or currently breastfeeding.

Meanwhile, studies dating back to last year have found that pregnant people face higher risks of severe illness, death, and delivery complications if they contract covid-19. According to the CDC, more than 125,000 cases of covid-19 among pregnant people have been documented in the U.S. as of late September. Of these, more than 22,000 were hospitalized and 161 ultimately died. And with the latest wave of the pandemic fueled by the Delta variant that arrived this summer, the danger has gone up. In August alone, 22 Americans died while infected and pregnant.

Overall, 65% of Americans over 12 have gotten fully vaccinated. But the same is true for only 31% of pregnant people—a situation that prompted the CDC to issue this plea to the public.

“Pregnancy can be both a special time and also a stressful time—and pregnancy during a pandemic is an added concern for families,” said CDC director Rochelle Walensky in a statement accompanying the advisory. “I strongly encourage those who are pregnant or considering pregnancy to talk with their healthcare provider about the protective benefits of the covid-19 vaccine to keep their babies and themselves safe.”

The CDC is also asking local health agencies and health providers to chip in and do their part to encourage vaccination among pregnant people.

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California May Be First State To Try Treatment That Pays Meth Users Not To Use : Shots - Health News - NPR

At the San Francisco AIDS Foundation, staff members Tyrone Clifford (left) and Rick Andrews (right) demonstrate how a contingency management visit typically begins, with a participant picking up a specimen cup for a urine sample. If the sample tests negative for meth or cocaine use, the participant has an incentive dollar amount added to their "bank" which can later be traded for a gift card. Christopher Artalejo-Price/San Francisco AIDS Foundation

Christopher Artalejo-Price/San Francisco AIDS Foundation

When Billy Lemon was trying to kick his methamphetamine addiction, he went to a drug treatment program at the San Francisco AIDS Foundation three times a week and peed in a cup. If it tested negative for meth, he got paid about $7.

"For somebody who had not had any legitimate money – without committing felonies – that seemed like a cool thing," says Lemon, who was arrested three times for selling meth before starting recovery.

The payments were part of a formal addiction treatment called contingency management, which incentivizes drug users with money or gift cards to stay off drugs. At the end of 12 weeks, after all his drug tests came back negative for meth, Lemon received $330. But for him, it was about more than just the money. It was being told, good job.

"It was the first opportunity where I was like, I have self-worth, still. It's buried. This person sees it and is willing to give me seven dollars, just to take care of myself. That was very motivating," he says.

As overdoses and public health costs related to meth and cocaine continue to spiral in California, state officials are desperate for more effective treatment options and are pursuing legislation and appealing to federal regulators to make contingency management more widely available. Washington, Montana, and West Virginia are also exploring similar strategies.

Because studies show contingency management works. The principles of the treatment – positive reinforcement techniques, primarily – are used widely in weight loss, fitness programs, and in families, as parents coax their children into adopting good behaviors, rather than punishing them for poor behaviors.

Billy Lemon, 50, kicked his meth habit more than 9 years ago after taking part in a "contingency management" program for meth and cocaine users at the San Francisco AIDS Foundation. For every negative drug test, he earned a small amount of money. Lemon now runs the Castro Country Club, a recovery center in San Francisco. Beth LaBerge/KQED

Beth LaBerge/KQED

Research shows contingency management is the most effective treatment for meth or cocaine addiction, especially when combined with other behavioral therapy. At the San Francisco AIDS Foundation, 63% of people who participated in the program in 2019 stopped using meth entirely, and another 19% reduced their use.

The Department of Veterans Affairs has relied on the therapy to treat 5,600 vets over the last 10 years. Of the 73,000 urine samples collected in the VA program, 92% tested negative for drugs, according to Dominick DePhilippis, a clinical psychologist at the Philadelphia Center for Substance Addiction Treatment & Education who helped launch the VA's program.

"Patients often come to treatment ambivalent about change. Why? Because substance use is so seductive. It provides powerful, immediate reinforcement," DePhilippis says. "Whereas recovery, its immediate consequences, are often unpleasant: withdrawal symptoms, a clear-eyed view of the devastated landscape that is one's life."

Contingency management embraces this challenge head on, he adds, by offering immediate rewards and reinforcement for abstinence. The small payments or prizes aim to rewire the brain's reward system, so the person seeks the money or gift card to get a dopamine release, instead of meth or coke.

"You're like, 'Oh! Oh! I can feel good without the daily use of that substance. Let me try and go one more week,'" says Lemon. "And then all of a sudden, you're at 90 days and you've actually made a change."

Despite its effectiveness, the treatment is controversial. Critics have scoffed at the idea of paying drug users not to use drugs, calling it unethical or a bribe. Most insurers don't cover it. Neither do state Medicaid programs. The feds generally forbid them from offering financial incentives to patients, as a protection against fraud and waste, and state officials have interpreted that rule as prohibiting reimbursement for contingency management.

California will try to scale up an effective treatment for stimulant addiction

But as the drug epidemic continues to worsen throughout California and the nation, with overdoses from stimulants like meth tripling in recent years, state officials are questioning those policies and pushing for changes. Critics are softening their stance. A bill now on the governor's desk – SB 110 – would allow the state's Medicaid program to pay for contingency management services, with the goal of encouraging more drug treatment centers to offer it.

"We need to embrace this proven, effective approach to meth addiction, make it clearly legal and start reimbursing for it, so we can address this health epidemic," says state Sen. Scott Wiener (D-San Francisco), who sponsored the bill.

Wiener says he was surprised to see the bill pass the California legislature with near unanimous, bipartisan support.

"The Republicans love it," he says. "I didn't think they would, but they actually like it because there's an abstinence component to it: we pay you money and you abstain from using."

The state's Department of Health Care Services, which runs California's Medicaid program, is also on board. Department leaders have already asked federal regulators for explicit permission to offer contingency management through a statewide pilot project, and the feds appear poised to grant it.

Until quite recently, the federal government has been reluctant to relax rules that bar public health programs from offering contingency management. In 2020, during the Trump administration, treatment experts asked the U.S. Department of Health and Human Services to waive the rules for two years, but the agency refused.

"It's clear the [Trump] administration had minimal interest in looking at evidence or science, on a wide variety of topics," says Laura Thomas, director of harm reduction policy at the San Francisco AIDS Foundation, which helped sponsor the bill.

The Biden administration, on the other hand, specifically stated in its 2021 drug control policy that one of its main priorities is to "identify and address policy barriers related to contingency management."

As stimulant overdoses soar, California looks to a proven behavioral intervention

The need is urgent, explains Dr. Kelly Pfeifer, deputy director of behavioral health at the California Department of Health Care Services. In 2020, more Californians died from meth and cocaine overdoses than from fentanyl overdoses, and stimulant abuse is wreaking havoc on California's jails and courts, foster care, and hospitals.

"Which are obviously not only devastating to the person and the family, but very expensive for our health care system," Pfiefer says.

There's also an increasing sense of hopelessness among stimulant users, she adds, because of the lack of effective, available treatments. For opioid addiction, there are now three FDA-approved medication therapies: methadone, buprenorphine and naltrexone. For meth and coke, there are no such medications.

Making contingency management more widely available would make more people willing to seek treatment, Pfiefer says.

"Because people will see success stories," she says. "They'll see friends and family getting treatment and getting help and getting better."

One drawback of contingency management is that the benefits may dwindle once the active treatment ends. For that reason, some doctors believe the incentive treatment should be delivered continuously, in the same way that medication therapies for opioid use disorder are sometimes prescribed indefinitely. But new research indicates the benefits may last longer than previously thought. In a review of 23 previously published trials, researchers at the University of Connecticut found that people who participated in contingency management were 22% more likely to be abstinent 6 months after treatment ended than people who received other treatments.

For Billy Lemon, contingency management was just what he needed to jumpstart his recovery, and to stay the course in residential rehab. When he cashed out all his incentive payments, he used the $330 to buy himself a new cell phone.

"Because up until then, Breaking Bad-style is burner phones," he says, referring to the prepaid disposable phones drug sellers use, then discard, to avoid detection by the police. "My number was never the same."

Now, nine years later, he's still sober - he runs the Castro Country Club, a recovery space in San Francisco - and the number he got with his new phone is still his number.

"It's a nice reminder of what making good decisions for yourself can turn into," he says.

This story comes from NPR's health reporting partnership with KQED and Kaiser Health News.

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Covid-19 live updates: CDC says it's 'urgent' pregnant women get vaccinated - The Washington Post

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  1. Covid-19 live updates: CDC says it's 'urgent' pregnant women get vaccinated  The Washington Post
  2. CDC issues an 'urgent' warning for pregnant people to get vaccinated as new data show pregnancy almost doubles the risk of death from COVID-19  Yahoo! Voices
  3. TV5 News Update: Wednesday evening, September 29  WNEM TV5
  4. Biden officials split on Covid-19 boosters as they plot course for winter  POLITICO
  5. Bronx charter school hits 100 percent staff vaccination rate  PIX11 News
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As deaths rise, vaccine opponents find a foothold in Bosnia - Yahoo News

SARAJEVO, Bosnia-Herzegovina (AP) — Hospitals across Bosnia are again filling with COVID-19 patients gasping for air, and the country's pandemic death toll is rising. Yet vaccination sites are mostly empty and unused coronavirus vaccines are fast approaching their expiration dates.

When the European Union launched its mass vaccination campaign, non-member Bosnia struggled along with most other Balkan nations to get supplies. By late spring, however, hundreds of thousands of doses started pouring into the country.

But after an initial rush of people clamoring to get jabbed, demand for shots quickly slowed. It is now down to a trickle even though Bosnia has Europe's highest coronavirus mortality rate at 4.5%, according to Johns Hopkins University data.

Dr. Edin Drljevic, an infectious disease specialist at one of Bosnia’s largest hospitals, in Sarajevo, thinks the disconnect is partly a result of authorities failing to properly promote vaccination against COVID-19.

“At first, we only had negative publicity because of the failure to secure vaccines, but once the vaccines finally started arriving, mainly through donations, people became picky,” he said.

So far, just under 13% of Bosnia’s 3.3 million people have been fully vaccinated, among the lowest shares in Europe. Even people willing to get inoculated are putting off shots so they can choose the vaccine they want instead of receiving whichever one is available.

Bosnia currently administers the Pfizer-BioNTech, Sputnik V, Sinopharm and AstraZeneca vaccines. AstraZeneca's product, while the most widely available, appears to enjoy the least trust because of extensive news coverage when numerous European countries temporary suspended its use due to concerns about possible, rare side effects.

“The bottom line is, people are poorly informed and lack up-to-date knowledge,” Drljevic said.

With so few takers, over 50,000 AstraZeneca vaccine doses have already expired; an additional 350,000 doses are set to expire in October

The pandemic has amplified the many problems of the Balkan nation, which is still struggling to recover from a devastating interethnic war in 1992-95. Nearly half of Bosnia's people live under or close to the poverty line.

The country has an extreme shortage of doctors and nurses, as well as rampant public corruption. Several elected and appointed government officials are under investigation or on trial for suspected malfeasance in the procurement of needed medical equipment and supplies during the pandemic.

The high-profile cases make Bosnians susceptible to claims that their leaders are acting in concert with corrupt pharmaceutical companies and are “happy to sacrifice them” for personal gain, according to Slavo Kukic, a sociology professor at Mostar University in southern Bosnia.

“People in Bosnia generally distrust the authorities. They (have been) lied to and manipulated for the past 30 years, and it makes it easier (for the anti-vaccine movement) to convince them that it is wise to not protect themselves from the virus, that it is a risk worth taking,” Kukic said.

While vaccine hesitancy in Bosnia might be among the most extreme globally, the country is not the only one in Europe facing that problem.

The International Federation of Red Cross and Red Crescent Societies voiced concern Thursday at low immunization rates in parts of the continent, calling for urgent action to tackle vaccine hesitancy and misinformation.

In a press release, it warned that disinformation about vaccines’ side effects and potential risks, coupled with the introduction of vaccine passes was “sparking anger and violence” and has led to “concerning incidents against medical services, media and the general public” in the United Kingdom and numerous EU member including Italy, The Netherlands, Poland, Slovenia and France.

"Without addressing people’s concerns and fears, vaccines may not find their way into the arms of those most at risk, even where doses are available,” IFRC regional director for Europe Birgitte Bischoff Ebbesen said. “Increased community engagement is needed to tackle vaccine hesitancy, myths and disinformation.”

In Bosnia, health professionals and vaccine recipients note the absence of a coordinated, hard-hitting national campaign to counter vaccine hesitancy. There are no public service ads, billboards, incentives or mass mailings encouraging people to get vaccinated or advising them how to do it.

Meanwhile, activists with strong anti-vaccine opinions dominate the discussion on social networks and in the comment sections of news sites.

An opposition lawmaker, Lana Prlic, announced on Facebook last week that she had received her second dose of AstraZeneca vaccine and urged followers to get their shots as soon as possible “to protect themselves and others." Her post attracted over 28,000 comments in 24 hours, most of them filled with insults and misinformation.

Jagoda Savic, Bosnia’s most vocal anti-vaccination activist for over a decade, asserts with pride that her profile has grown during the pandemic.

“People stop me in the street to say hello, to congratulate me and ask me to keep up the good work,” she said. “I get so many messages (of support) on Facebook that I can no longer respond to all of them.”

Savic claims that coronavirus vaccines were not put through standard safety testing before being approved for use, and that they have caused severe adverse reactions in 1.2 million people in the European Union, the U.K. and the United States.

Similar claims have been made in other countries, and scientists and health authorities have repeatedly rejected them. Savic countered that information from reputable sources may cause doubts about the “dangers” of vaccines, but “in their heart and soul, people know the truth.”

Bosnia has reported close to 240,000 confirmed cases and more than 10,500 deaths in the pandemic. Savic asserts the figures are inflated, arguing incorrectly that that molecular PCR tests — the primary method for diagnosing COVID-19 — produce a huge number of false positives.

“Unfortunately, I have the impression that we are simply letting anti-vaccination lobbies and movements highjack the public debate and spread misinformation that discourages people from getting immunized,” Bakir Nakas, a retired infectious disease specialist, said.

While waiting to get her second coronavirus vaccine shot in Sarajevo last week, cancer patient Mirjana Golijanin said she thinks some fellow Bosnians are refusing because they perceive such behavior as a way of opposing the powerful and rich.

“I think it is simply an expression of the need to offer some sort of resistance, even if all they are resisting is a vaccine,” Golijanin said.

___

Follow all of AP’s pandemic coverage at https://apnews.com/hub/coronavirus-pandemic

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Wednesday, September 29, 2021

C.D.C. Pleas for Pregnant or Breastfeeding People to Get Vaccinated - The New York Times

In an urgent plea on Wednesday, federal health officials asked that any American who is pregnant, planning to become pregnant or currently breastfeeding get vaccinated against the coronavirus as soon as possible.

Covid-19 poses a severe risk during pregnancy, when an individual’s immune system is tamped down, and raises the risk of stillbirth or another poor outcome, according to the Centers for Disease Control and Prevention. Twenty-two pregnant individuals in the United States died of Covid in August, the highest number in a single month since the pandemic started.

Some 125,000 pregnant people have tested positive for the virus; 22,000 of them have been hospitalized, and 161 have died. Hospital data indicates that 97 percent of those who were infected with the virus when they were hospitalized — for illness, or for labor and delivery — were not vaccinated.

Vaccination rates among those who are pregnant are lower than among the general population. Fewer than one-third of all pregnant people were vaccinated before or during their pregnancy, the agency said.

The rates vary widely by race and ethnicity, with the highest — nearly 50 percent — among pregnant Asian American individuals, and the lowest rates among pregnant Black individuals, at just 15 percent.

Pregnancy is on the C.D.C.’s list of health conditions that increase the risk of severe Covid. Though the absolute risk of severe disease is low, pregnant patients who are symptomatic are more than twice as likely as other symptomatic patients to require admission to intensive care or interventions like mechanical ventilation, and may be more likely to die.

Some data also suggest that pregnant individuals with Covid-19 are more likely to experience conditions that complicate pregnancy — like a kind of high blood pressure called pre-eclampsia — compared with pregnant individuals who don’t have Covid. Pregnant individuals with the disease are also at increased risk for poor birth outcomes, like preterm birth.

Clinical trials have a long history of excluding those who are pregnant from participation, and pregnant individuals were not included in the coronavirus vaccine trials. As a result, data on the safety and effectiveness of vaccines is limited in this group.

Studies conducted since the vaccines were authorized, however, have shown that the vaccines do not increase the risk of a miscarriage. Both the Pfizer-BioNTech and Moderna vaccines produced robust immune responses in those who are pregnant, and did not damage the placenta, researchers have found.

“Pregnancy can be both a special time and also a stressful time, and pregnancy during a pandemic is an added concern for family,” said Dr. Rochelle Walensky, the director of the C.D.C. She encouraged those who are pregnant and those who may become pregnant “to talk with their health care provider about the protective benefits of the Covid-19 vaccine to keep their babies and themselves safe.”

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YouTube bans all anti-vaccine content, not just COVID-19-related - New York Post

YouTube is banning several prominent anti-vaxxers from its site — including Robert F. Kennedy Jr. — and will delete all content that suggests approved vaccines are harmful or don’t work, the company said Wednesday.

The online video platform, which is owned by Google, said in a blog post it is cracking down on content that falsely claims vaccines can cause chronic health effects.

It is also targeting content that includes misinformation on the contents of approved vaccines.

The new ban applies to all vaccines — not just those for COVID-19.

Among the channels being removed under the new policy is Robert F. Kennedy Jr.’s Children’s Health Defense Fund, a YouTube spokesperson told the Post.

Channels belonging to author Joseph Mercola, health blogger Erin Elizabeth and Ohio doctor Sherri Tenpenny are also being removed.

Robert F. Kennedy Jr
YouTube is banning Robert F. Kennedy Jr.’s Children’s Health Defense Fund from the site.
Sean Gallup/Getty Images

Instagram yanked RFK Jr.’s account back in February over his bogus COVID vaccine claims.

YouTube had already put in place a similar ban related to COVID-19 vaccine misinformation amid the pandemic.

The company said it is putting the wider ban in place after seeing false claims about the COVID-19 vaccine spread to misinformation about vaccines in general.

Several thousand anti-vaccine protestors march through the streets of Manhattan, on September 18, 2021.
Several thousand anti-vaccine protesters march through the streets of Manhattan, on September 18, 2021.
Andrew Lichtenstein/Corbis via Getty Images

“Content that falsely alleges that approved vaccines are dangerous and cause chronic health effects, claims that vaccines do not reduce transmission or contraction of disease, or contains misinformation on the substances contained in vaccines will be removed,” the company said.

Robert Kennedy Jr., left, stands with participants at a rally held in opposition to a proposed bill that would remove parents' ability to claim a philosophical exemption to opt their school-age children out of the combined measles, mumps and rubella vaccine, at the Capitol in Olympia, Wash.
Robert Kennedy Jr., left, stands with participants at a rally held in opposition to a proposed bill that would remove parents’ ability to claim a philosophical exemption to opt their school-age children out of the combined measles, mumps and rubella vaccine, at the Capitol in Olympia, Wash.AP

“This would include content that falsely says that approved vaccines cause autism, cancer or infertility, or that substances in vaccines can track those who receive them. Our policies not only cover specific routine immunizations like for measles or Hepatitis B, but also apply to general statements about vaccines.”

The ban does not apply to content about vaccine policies, new vaccine trials, and historical vaccine successes or failures, the company said.

Anti-vax protesters demonstrate outside of the San Diego Unified School District office to protest a forced vaccination mandate for students, on September 28, 2021.
Anti-vax protesters demonstrate outside the San Diego Unified School District office to protest a vaccination mandate for students, on September 28, 2021.
Sandy Huffaker/Getty Images

“Personal testimonials relating to vaccines will also be allowed, so long as the video doesn’t violate other Community Guidelines, or the channel doesn’t show a pattern of promoting vaccine hesitancy,” YouTube said.

YouTube said it had removed more than 130,000 videos for violating COVID-19 vaccine policies within the last year.

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Weight Gain And Obesity Up In 2020 In The US : Shots - Health News - NPR

A Planet Fitness employee cleans equipment before a gym's reopening in March in Inglewood, Calif., after being closed due to COVID-19. Reduced access to recreation likely has contributed to weight gain during the pandemic. Patrick T. Fallon/AFP via Getty Images

Patrick T. Fallon/AFP via Getty Images

It is official: The pandemic's effect on America's waistline has been rough.

New data from the Centers for Disease Control and Prevention showed 16 states now have obesity rates of 35% or higher. That's an increase of four states — Delaware, Iowa, Ohio and Texas — in just a year.

The findings confirm what several recent research studies have found: Many Americans have gained significant weight since the COVID-19 crisis started, likely fueled by an increase in sedentary behavior, stress and troubles such as job and income loss that make healthy eating harder.

And those rates are rising faster among racial minorities.

"Obesity continues to be a significant public health crisis," says Nadine Gracia, a physician and president and CEO of Trust for America's Health, a health policy group that recently analyzed the CDC's 2020 data. And growth in childhood obesity, she says, projects a worsening trend.

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The pandemic only exacerbated a problem that was already quickly accelerating in the last decade. In 2011, not a single state had reached the threshold of 35% obesity. Now, among the 16 at that level, a handful are close to 40%. The rates are higher in the South and Midwest.

Stress and rising weight

The latest CDC data is based on a survey of people self-reporting their own height and weight, so if anything, the new data likely understates the problem, says Dr. Fatima Cody Stanford, a leading obesity researcher at Harvard Medical School.

"When patients are reporting or individuals are reporting their weight, they tend to underreport. So I think that this report will under-capture, actually, the degree of obesity in the U.S.," she says.

Stanford argues that obesity's growing prevalence has not met with adequate recognition that it is a disease. And because it goes largely unrecognized or untreated, it does not surprise her it continues to increase — especially during difficult times such as the last year and half of the pandemic and its economic and social fallout.

"When we look at factors that play a role in rising obesity, we know stress is one of them," she says.

She says stress doesn't just affect exercise and eating patterns. It also prompts the body to store more fat. During the pandemic, other factors, including food insecurity and reduced access to recreation made it more likely that everyone from children to older adults would gain weight.

Other research supports the finding that obesity rates increased in the pandemic. A March survey from the American Psychological Association found 42% of Americans said they had gained more weight than intended, 29 pounds on average. A recent study that gathered data from pediatric health records found a trend of weight gain among children, especially those ages 5 to 11. Among that age group, overweight or obesity increased from 36.2% to 45.7% during the pandemic.

The pandemic revealed how the growth in obesity threatens the health of both individuals and the health care system. It makes people more vulnerable to hospitalization and death from COVID-19. At the same time, the pandemic worsened many of the social and economic factors that cause obesity, too. Job or income loss, for example, often means families cannot afford healthier food options.

Gracia of Trust for America's Health says with obesity comes the threat of diabetes, heart or kidney disease, and cancer. That adds to an enormous financial cost.

"We spend about $149 billion a year on health care costs that are obesity-related," she says.

Finding solutions to racial inequities

There are big racial differences in the impact of obesity: A separate CDC survey from 2017-2018 showed nearly half of Black people and 57% of Black women have obesity. In the Latino population, the rate is nearly 45%; among white adults, 42%. Asian adults had the lowest rate at 17%.

More minority families shouldered the economic brunt of the pandemic, says Dr. Elena Rios, president and CEO of the National Hispanic Medical Association, because they represent a greater share of the low-wage or essential workforce.

"I mean, there's just so much pressure on low-income families," she says. "Everybody has to pitch in and do something, [so] they don't take care of their health."

Gracia says larger investments in healthier school meals and greater access to recreation are necessary to combat the growing problem. Minority communities especially need greater access to health insurance and medical care.

"Being able to access those services is important to receiving preventative services, counseling and supports to address obesity," she says.

There are other community factors Rios points to as well: fewer local options for healthy food and less access to health insurance and care. And these factors can have a dire effect on people's health.

"Our communities don't get the messages that you're going to have diabetes earlier, you're going to have heart disease earlier in your life and by the time you're in your 30s and 40s, you're going to be on dialysis. That's the trend that's happening in our communities," she says.

Given the stigma around obesity, crafting messages that resonate is not easy, says Tammy Boyd, chief policy officer of the Black Women's Health Imperative.

"It's a very delicate balance," she says, because using words such as "weight" easily sounds stigmatizing. But at the same time, Boyd says, the community needs to understand obesity as a critical health and wellness issue.

For Boyd, one of the most promising potential remedies is medication. New classes of drugs are proving both safer and more effective than what's been on the market.

Most insurance — including Medicare — does not cover them. Congress is considering a bill allowing Medicare to cover obesity drugs and behavioral counseling. Boyd says if the legislation passes, many other insurers would likely follow. And that might help curb some of the disturbing trend lines.

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Vaccination increase includes largest Republican gain since April: Gallup - The Hill

An increase in Americans who say they are vaccinated against COVID-19 includes the largest Republican gain since April, according to a Gallup poll released Wednesday.

Seventy-five percent of respondents said they were vaccinated against COVID-19, up 6 points from August. 

Overall, 80 percent said they either are vaccinated or plan to be vaccinated, the highest tally this year.

For the first time, a majority of Republicans responded that they had received at least one dose of a coronavirus vaccine, the largest monthly uptick from April, when 39 percent said they had been at least partially vaccinated.   

By comparison, 68 percent of independents and 92 percent of Democrats said they are at least partially vaccinated against COVID-19.

The increase in Americans saying they are vaccinated comes amid an uptick in coronavirus infections fueled by the delta variant, which has disproportionately impacted areas of the country with lower vaccination rates overall.

Late last month, the Food and Drug Administration granted full approval Pfizer-BioNTech vaccine. Gallup noted that it found a sharp decline in unvaccinated Americans saying they were waiting for a vaccine to receive full approval. 

Earlier this month, President BidenJoe BidenVaccination increase includes largest Republican gain since April: Gallup Power grab? The Federal Reserve soon may be our only bank Ford asking salaried workers for vaccination status MORE required all federal workers to be vaccinated and mandated employers with at least 100 employees to require vaccinations or weekly testing.

While Gallup said it’s too soon for Biden’s policy to affect the vaccination rate of workers, the poll did find that 75 percent of Americans who are employed full-time or part-time are at least partially vaccinated.

This is similar to the percentage of the U.S. population ages 12 and older who have received at least one dose.

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Merck Says Its Covid-19 Antiviral Pill Looks Good Against Variants - Barron's

Capsules of Merck's Covid-19 antiviral molnupiravir.

Courtesy Merck

Merck presented a study at a medical conference early Wednesday showing that its experimental Covid-19 antiviral is active against variants of the virus that causes the sickness.

The Merck product, known as molnupiravir, is one of a number of antiviral pills under development to treat and even prevent Covid-19. Pivotal data on some of the pills, including those from Merck (ticker: MRK) and from Pfizer (PFE), is likely to be available soon. Executives from both companies have said they plan to file for emergency-use authorization before the end of the year.

As Barron’s reported in a magazine feature earlier this month, the pills have the potential to play an enormous role as the world adapts to an endemic threat from Covid-19. Even if the antivirals from Merck, Pfizer, the biotech Atea Pharmaceuticals (AVIR), and others, are only moderately effective, they are likely to be in enormous demand globally as patients and governments seek to blunt the human toll of the virus.

Currently available therapeutics for Covid-19, including the monoclonal antibody therapies from GlaxoSmithKline (GSK), Regeneron Pharmaceuticals (REGN), and others, are generally administered intravenously, which makes them inconvenient for widespread use. Pills would allow for much broader access.

The new study from Merck answers one vital question about the antiviral pills: Would their efficacy be weakened by the rapid mutation of the virus, as has happened with the Covid-19 vaccines?

The study, presented at IDWeek 2021, a medical conference focusing on infectious diseases, examined data from two separate clinical trials of molnupiravir and in vitro studies of the drug. The authors found that mutations of the spike protein of the SARS-CoV-2 virus didn’t impact the work of the drug against the virus.

“Both in vitro and clinical data suggest that spike protein substitutions do not impact antiviral activity of [molnupiravir] and suggest molnupiravir’s potential for the treatment of SARSCoV-2 variants, particularly when initiated early in the course of illness,” the authors wrote.

The response to the drug was greatest in patients who had been symptomatic for five days or fewer when they began treatment, they said.

Merck, which is developing molnupiravir in partnership with the private firm Ridgeback Biotherapeutics, is running Phase 3 trials of the drug as a post-exposure prophylaxis, and in non-hospitalized adults. In April, the company said it had decided not to proceed with a study of molnupiravir in hospitalized patients after disappointing early results.

Earlier this week, Pfizer said it had begun testing its experimental Covid-19 antiviral, known as PF-07321332, as a post-exposure prophylaxis. Pfizer is also running other studies of the drug in non-hospitalized patients.

Write to Josh Nathan-Kazis at josh.nathan-kazis@barrons.com

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